BDBM425048 N-[(2S)-5-[[(1R,2S)-2-(4- Fluorophenyl)cyclopropyl]amino]-1-(4- methylpiperazin-1-yl)-1-oxopentan-2-yl]-4- (1H-1,2,3,4-tetrazol-1-yl)benzamide::US10519118, Example 120::US11230534, Example 120

SMILES CN1CCN(CC1)C(=O)[C@H](CCCN[C@@H]1C[C@H]1c1ccc(F)cc1)NC(=O)c1ccc(cc1)-n1cnnn1

InChI Key InChIKey=TYYKEJWRYCVYDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425048   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425048(US10519118, Example 120 | N-[(2S)-5-[[(1R,2S)-2-(4...)
Affinity DataIC50: 7.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425048(US10519118, Example 120 | N-[(2S)-5-[[(1R,2S)-2-(4...)
Affinity DataIC50: 7.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent