BDBM425038 N-[(2S)-1-[4-(2-Cyanoacetyl)piperazin-1- yl]-5-[[(1R,2S)-2-(4- fluorophenyl)cyclopropyl]amino]-1- oxopentan-2-yl]-4-(1H-1,2,3-triazol-1- yl)benzamide::US10519118, Example 107::US11230534, Example 107

SMILES Fc1ccc(cc1)[C@@H]1C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1ccnn1)C(=O)N1CCN(CC1)C(=O)CC#N

InChI Key InChIKey=VEIFIGSANRZJQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425038   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425038(US10519118, Example 107 | N-[(2S)-1-[4-(2-Cyanoace...)
Affinity DataIC50: 5.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425038(US10519118, Example 107 | N-[(2S)-1-[4-(2-Cyanoace...)
Affinity DataIC50: 5.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent