BDBM425028 4-(Dimethylsulfamoyl)-N-[(2S)-5- [[(1R,2S)-2-(4- fluorophenyl)cyclopropyl]amino]-1-(4- methylpiperazin-1-yl)-1-oxopentan-2- yl]benzamide::US10519118, Example 96::US11230534, Example 96

SMILES CN(C)S(=O)(=O)c1ccc(cc1)C(=O)N[C@@H](CCCN[C@@H]1C[C@H]1c1ccc(F)cc1)C(=O)N1CCN(C)CC1

InChI Key InChIKey=JBRFAYTUUXDYDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425028   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425028(US10519118, Example 96 | 4-(Dimethylsulfamoyl)-N-[...)
Affinity DataIC50: 8.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM425028(US10519118, Example 96 | 4-(Dimethylsulfamoyl)-N-[...)
Affinity DataIC50: 8.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent