BDBM424980 N-[(2S)-5-[[(1R,2S)-2-(4- fluorophenyl)cyclopropyl]amino]-1-(4- methyl-3-oxopiperazin-1-yl)-1-oxopentan- 2-yl]-4-(1,2,3-triazol--yl)benzamide::US10519118, Example 51::US11230534, Example 51

SMILES Fc1ccc(cc1)[C@@H]1C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1ccnn1)C(=O)N1CCNC(=O)C1

InChI Key InChIKey=ITJLDERHNAQWSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 424980   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424980(US10519118, Example 51 | N-[(2S)-5-[[(1R,2S)-2-(4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424980(US10519118, Example 51 | N-[(2S)-5-[[(1R,2S)-2-(4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent