BDBM424966 N-[(2S)-1-(3-cyanoazetidin-1-yl)-5- [[(1R,2S)-2-(4- fluorophenyl)cyclopropyl]amino]-1- oxopentan-2-yl]-4-(1H-pyrazol-1- yl)benzamide::US10519118, Example 35::US11230534, Example 35

SMILES Fc1ccc(cc1)[C@@H]1C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1cccn1)C(=O)N1CC(C1)C#N

InChI Key InChIKey=WWHHAMSKHFGBKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 424966   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424966(US10519118, Example 35 | N-[(2S)-1-(3-cyanoazetidi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424966(US10519118, Example 35 | N-[(2S)-1-(3-cyanoazetidi...)
Affinity DataIC50: 3.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent