BDBM424951 N-((S)-4-((1R,2S)-2-(4- methoxyphenyl)cyclopropylamino)-1-oxo- 1-(thiomorpholino-4,4-dioxide-1-yl)-butan- 2-yl)biphenyl-4-carboxamide::US10519118, Example 19::US11230534, Example 19

SMILES COc1ccc(cc1)[C@@H]1C[C@H]1NCC[C@H](NC(=O)c1ccc(cc1)-c1ccccc1)C(=O)N1CCS(=O)(=O)CC1

InChI Key InChIKey=YNQACKPLPJNFOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 424951   

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424951(US10519118, Example 19 | N-((S)-4-((1R,2S)-2-(4- m...)
Affinity DataIC50: 3.00E+3nMAssay Description:Briefly, bulk histones, histone peptides or nucleosomes are incubated with purified human recombinant KDM1A, in the histone demethylase activity (HDM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Imago Biosciences

US Patent
LigandPNGBDBM424951(US10519118, Example 19 | N-((S)-4-((1R,2S)-2-(4- m...)
Affinity DataIC50: 3.00E+3nMAssay Description:The KDM1A demethylase enzyme activity can obtained from mammalian cells or tissues expressing KDM1A from an endogenous or recombinant gene and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
Go to US Patent