BDBM423485 US10508115, Compound Ib-04

SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5CCC5)cc4)nc3)c2n1

InChI Key InChIKey=HXZUISIFKJUFSH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423485   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423485(US10508115, Compound Ib-04)
Affinity DataEC50:  0.910nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2020
Entry Details
US Patent