BDBM423325 US10501452, Compound 31

SMILES Cc1nc2ccc(OCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)cc2c(=O)n1C

InChI Key InChIKey=ZHBTYBBXWTXWRS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 423325   

Target5-hydroxytryptamine receptor 7(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi:  8.30nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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Target5-hydroxytryptamine receptor 2A(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi:  9.80nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 1A(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi:  19nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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TargetD(2) dopamine receptor(Human)
Nhwa Pharma.

US Patent
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi:  21.8nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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TargetHistamine H1 receptor(Rat)
Nhwa Pharma.

US Patent
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi: >2.00E+3nMAssay Description:Histamine H1: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent