BDBM423217 5-((2R,6S)-4-((2- (4,5-dimethyl-1H- imidazol-1- yl)pyrimidin-5- yl)methyl)-6- methylpiperazin-2- yl)-4- methylisobenzofuran- 1(3H)-one::US10501449, Example 94-I

SMILES C[C@H]1CN(Cc2cnc(nc2)-n2cnc(C)c2C)C[C@H](N1)c1ccc2C(=O)OCc2c1C

InChI Key InChIKey=UTGZFFHEBYYJLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423217   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423217(US10501449, Example 94-I | 5-((2R,6S)-4-((2- (4,5-...)
Affinity DataIC50: 14nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
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Date in BDB:
10/12/2020
Entry Details
US Patent