BDBM423196 1-[6-(2-Aza-spiro[3.3]hept-2-yl)-2-methyl-pyridin-3-ylmethyl]-1H-pyrazole-4-carboxylic acid ((R)-1-amino-6,7-dihydro-5H-[2]pyrindin-5-yl)-amide::US10501440, Example 25

SMILES Cc1nc(ccc1Cn1cc(cn1)C(=O)N[C@@H]1CCc2c1ccnc2N)N1CC2(CCC2)C1

InChI Key InChIKey=HPGCPAWAPHBCPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423196   

TargetPlasma kallikrein(Rat)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423196(US10501440, Example 25 | 1-[6-(2-Aza-spiro[3.3]hep...)
Affinity DataIC50: 2.10nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
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Date in BDB:
10/12/2020
Entry Details
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