BDBM423193 N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl]-1-[(6-{3-azabicyclo[3.1.0]hexan-3-yl}-2-methylpyridin-3-yl)methyl]-3-methoxy-1H-pyrazole-4-carboxamide::US10501440, Example 22

SMILES COc1nn(Cc2ccc(nc2C)N2CC3CC3C2)cc1C(=O)N[C@@H]1CCc2c1ccnc2N

InChI Key InChIKey=ZEFCQWNRSFKRBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423193   

TargetPlasma kallikrein(Rat)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423193(US10501440, Example 22 | N-[(5R)-1-Amino-5H,6H,7H-...)
Affinity DataIC50: 1.10nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
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Date in BDB:
10/12/2020
Entry Details
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