BDBM423177 US10501440, Example 8

SMILES Cc1nc(ccc1Cn1cc(nn1)C(=O)N[C@@H]1CCc2c1ccnc2N)N1CC2C(C1)C2(F)F

InChI Key InChIKey=HDCODOAKCTZNLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423177   

TargetPlasma kallikrein(Rat)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423177(US10501440, Example 8)
Affinity DataIC50: 5.5nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent