BDBM422693 US10508105, Compound 110::US10508105, Compound 114::US10508105, Compound 42

SMILES Cn1nc(OCC2CCOC2)c2ccc(NC(=O)c3ccccn3)cc12

InChI Key InChIKey=PDWGGZAKLOYDTN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 422693   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422693(US10508105, Compound 110 | US10508105, Compound 11...)
Affinity DataEC50:  81.2nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422693(US10508105, Compound 110 | US10508105, Compound 11...)
Affinity DataEC50:  50.4nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM422693(US10508105, Compound 110 | US10508105, Compound 11...)
Affinity DataEC50:  81.2nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent