BDBM422158 2-butyl-1-(2,6- dimethoxyphenyl)-6- hydroxy-5-{4-[2- (methoxymethyl)phenyl] benzenesulfonyl}-1,4- dihydropyrimidin-4-one::US10508104, Example 49

SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1ccccc1COC

InChI Key InChIKey=FRSRBGHTZVVAIG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422158   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422158(2-butyl-1-(2,6- dimethoxyphenyl)-6- hydroxy-5-{4-[...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent