BDBM422136 2-butyl-1-(2,6- dimethoxyphenyl)-6- hydroxy-5-{4-[6- (morpholin-4- yl)pyridin-3- yl]benzenesulfonyl}- 1,4-dihydropyrimidin-4- one::US10508104, Example 28

SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1ccc(nc1)N1CCOCC1

InChI Key InChIKey=RKUUYROXMBSMNM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422136   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422136(US10508104, Example 28 | 2-butyl-1-(2,6- dimethoxy...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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