BDBM422128 1-(2,6- dimethoxyphenyl)-5-[2- (4- fluorophenyl)benzene- sulfonyl]-6-hydroxy-2-(3- methylbutyl)-1,4- dihydropyrimidin-4-one::US10508104, Example 21

SMILES COc1cccc(OC)c1-n1c(O)c(c(=O)nc1CCC(C)C)S(=O)(=O)c1ccccc1-c1ccc(F)cc1

InChI Key InChIKey=VBCXFZUIRKRRMI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422128   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422128(US10508104, Example 21 | 1-(2,6- dimethoxyphenyl)-...)
Affinity DataEC50:  55nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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