BDBM422124 5-(4-{[1-(2,6- dimethoxyphenyl)-6- hydroxy-2-(3- methylbutyl)-4-oxo-1,4- dihydropyrimidin-5- yl]sulfonyl}phenyl)pyri- dine-2-carbonitrile::US10508104, Example 17

SMILES COc1cccc(OC)c1-n1c(CCC(C)C)nc(=O)c(c1O)S(=O)(=O)c1ccc(cc1)-c1ccc(nc1)C#N

InChI Key InChIKey=HAQOIYUZRPLYHZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422124   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422124(US10508104, Example 17 | 5-(4-{[1-(2,6- dimethoxyp...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
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