BDBM422121 5-[4-(4- chlorophenyl)benzene- sulfonyl]-1-(2,6- dimethoxyphenyl)-6- hydroxy-2-(3- methylbutyl)-1,4- dihydropyrimidin-4-one::US10508104, Example 14

SMILES COc1cccc(OC)c1-n1c(O)c(c(=O)nc1CCC(C)C)S(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=JPNNVXSZAQMYML-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422121   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422121(US10508104, Example 14 | 5-[4-(4- chlorophenyl)ben...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent