BDBM422095 US10508103, Embodiment 10

SMILES CCC[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1Cn1c(nc2cc(F)ccc12)-c1[nH]c2cc(F)ccc2c1C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C

InChI Key InChIKey=OHIQIMJKIOFHNP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422095   

TargetTumor necrosis factor(Human)
Medshine Discovery

US Patent
LigandPNGBDBM422095(US10508103, Embodiment 10)
Affinity DataEC50:  55nMAssay Description:First day:Dilution of Compounds: 1) tested compounds were added into DMSO to give parent liquor (10 mM); 2) reference compound Birinapant (32 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent