BDBM421692 3-((5-chloro-6-nitro-1H-benzo[d]imidazol- 2-yl)amino)-N-hydroxybenzamide::BDBM429847::US10508088, Example 33-15

SMILES ONC(=O)c1cccc(Nc2nc3cc(Cl)c(cc3[nH]2)[N+]([O-])=O)c1

InChI Key InChIKey=IMKQNWHCISUVPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421692   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421692(3-((5-chloro-6-nitro-1H-benzo[d]imidazol- 2-yl)ami...)
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421692(3-((5-chloro-6-nitro-1H-benzo[d]imidazol- 2-yl)ami...)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
Go to US Patent