BDBM421679 3-((5-chloro-6-methyl-1H- benzo[d]imidazol-2-yl)amino)-N- hydroxybenzamide::US10508088, Example 33-2::US10538496, Compound 33-2

SMILES Cc1cc2[nH]c(Nc3cccc(c3)C(=O)NO)nc2cc1Cl

InChI Key InChIKey=SYWLJRWSPXZGKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421679   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421679(US10538496, Compound 33-2 | US10508088, Example 33...)
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421679(US10538496, Compound 33-2 | US10508088, Example 33...)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
Go to US Patent