BDBM420985 US9975885, Compound 38

SMILES CC(C)Cc1ccc(cc1)N(C(C(=O)NC(C)(C)C)c1cccnc1)C(=O)c1c[nH]cn1

InChI Key InChIKey=DOAKTUQWUJZWRQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 420985   

TargetReplicase polyprotein 1ab(FCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 6.11E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(PEDV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 1.55E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-HKU1)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 1.54E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 2.44E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 7.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(BtCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 7.70E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(BtCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 1.09E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(BtCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50: 1.80E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent