BDBM42062 2,3-dihydro-1,4-benzodioxin-3-ylmethyl(thieno[2,3-d]pyrimidin-4-yl)amine::MLS000389009::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-thieno[2,3-d]pyrimidinamine::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)thieno[2,3-d]pyrimidin-4-amine::SMR000255183::cid_3457853

SMILES C(Nc1ncnc2sccc12)C1COc2ccccc2O1

InChI Key InChIKey=RRLUKZIJKWOVBH-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 42062   

TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataIC50: 4.20E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataIC50: 4.20E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataEC50:  4.18E+4nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataEC50:  4.16E+4nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetZinc finger protein GLI1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataIC50: 887nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetProtein Wnt-3a(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM42062(cid_3457853 | N-(2,3-dihydro-1,4-benzodioxin-3-ylm...)
Affinity DataIC50: 1.83E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay