BDBM42055 (E)-2-(1H-benzimidazol-2-yl)-3-(2-thienyl)acrylonitrile::(E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-2-propenenitrile::(E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-prop-2-enenitrile::(E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile::2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acrylonitrile::MLS000567024::SMR000175048::cid_5334847

SMILES N#C\C(=C/c1cccs1)c1nc2ccccc2[nH]1

InChI Key InChIKey=MDVSLHGZTWHJMW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 42055   

TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42055(2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acryloni...)
Affinity DataIC50: 4.20E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42055(2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acryloni...)
Affinity DataIC50: 4.20E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetLethal factor(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM42055(2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acryloni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis lethal factor using MCA-KKVYPYPME[dnp]Kamide peptide substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM42055(2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acryloni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage after 40 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed