BDBM420323 US10472354, Example 384

SMILES C[C@@H](NC(=O)c1cc(OC[C@H]2CN(C)CCC2(F)F)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=LGPVNMAGAZJDEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420323   

TargetP2X purinoceptor 3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM420323(US10472354, Example 384)
Affinity DataIC50: 3nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/14/2020
Entry Details
Go to US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM420323(US10472354, Example 384)
Affinity DataIC50: 75nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/14/2020
Entry Details
Go to US Patent