BDBM420319 5 Chloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-[(2-hydroxy-1-methylethyl)amino]-2-methylbenzamide::US10478426, Example 26

SMILES CC(CO)Nc1cc(Cl)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=ACFSELABMAJBKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420319   

LigandPNGBDBM420319(5 Chloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
Entry Details
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