BDBM420312 5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-{[6-methyl-2-oxo-4-(phenylmethyl)-1,2-dihydro-3-pyridinyl]methyl}benzamide::US10478426, Example 4

SMILES CC(C)Nc1cc(Br)cc(C(=O)NCc2c(Cc3ccccc3)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=SNUWAWGCYPMRAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420312   

LigandPNGBDBM420312(5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-{[6-me...)
Affinity DataIC50: 50nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
Entry Details
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