BDBM420120 US10487086, Example II-13

SMILES COC(=O)Nc1ccc-2c(NC(CCCC[C@H](NC(=O)[C@H]3CC[C@H](CN)CC3)c3cc-2ccn3)C(F)(F)F)c1

InChI Key InChIKey=YTPPZSNWCBWWTL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420120   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420120(US10487086, Example II-13)
Affinity DataKi: <5nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
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