BDBM419315 (3S)-1-[5-tert-Butyl-2-[[2-ethynyl-6-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-ol::US10457686, Example 6

SMILES CC(C)(C)c1nc(N2CC[C@H](O)C2)c2nn(Cc3c(cccc3C3(N=N3)C(F)(F)F)C#C)nc2n1

InChI Key InChIKey=VUGSAERAUZMIMX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419315   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419315((3S)-1-[5-tert-Butyl-2-[[2-ethynyl-6-[3-(trifluoro...)
Affinity DataKi:  99.2nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419315((3S)-1-[5-tert-Butyl-2-[[2-ethynyl-6-[3-(trifluoro...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent