BDBM419313 5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrrolidin-1-yl)-2-[[2-ethynyl-6-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]triazolo[4,5-d]pyrimidine::US10457686, Example 4

SMILES FC(F)(F)C1(N=N1)c1cccc(C#C)c1Cn1nc2nc(nc(N3CCC(F)(F)C3)c2n1)C(F)(F)c1ccccc1

InChI Key InChIKey=NFXAIKGZPMXHTQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419313   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419313(5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataKi:  1.07E+3nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419313(5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent