BDBM419308 5-tert-butyl-7-(3,3-Difluoropyrrolidin-1-yl)-3-[[2-(pyridin-2-yldisulfanyl)phenyl]methyl]triazolo[4,5-d]pyrimidine::US10457685, Example 37

SMILES CC(C)(C)c1cc(N2CCC(F)(F)C2)c2nnn(Cc3ccccc3SSc3ccccn3)c2n1

InChI Key InChIKey=XXQYHMLSXSXKMW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419308   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419308(5-tert-butyl-7-(3,3-Difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataKi:  541nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419308(5-tert-butyl-7-(3,3-Difluoropyrrolidin-1-yl)-3-[[2...)
Affinity DataKi:  2.58E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent