BDBM419297 2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrrolidin-1-yl)triazolo[4,5-d]pyrimidin-3-yl]methyl]benzenesulfonyl fluoride::US10457685, Example 26

SMILES FC(F)(c1ccccc1)c1nc(N2CCC(F)(F)C2)c2nnn(Cc3ccccc3S(F)(=O)=O)c2n1

InChI Key InChIKey=YLPSAOYZKVCQKO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419297   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419297(2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrr...)
Affinity DataKi:  630nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419297(2-[[5-[Difluoro(phenyl)methyl]-7-(3,3-difluoropyrr...)
Affinity DataKi: >1.00E+4nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent