BDBM419294 5-[Difluoro(phenyl)methyl]-7-(3-isothiocyanatopyrrolidin-1-yl)-3-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidine::US10457685, Example 23

SMILES Cc1nonc1Cn1nnc2c(nc(nc12)C(F)(F)c1ccccc1)N1CCC(C1)N=C=S

InChI Key InChIKey=WODTUUKLNRBZQF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419294   

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419294(5-[Difluoro(phenyl)methyl]-7-(3-isothiocyanatopyrr...)
Affinity DataKi:  1.45E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419294(5-[Difluoro(phenyl)methyl]-7-(3-isothiocyanatopyrr...)
Affinity DataKi:  1.46E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent