BDBM419286 5-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3-isothiocyanatopyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine::US10457685, Example 15

SMILES CC(C)(C)c1nc(N2CCC(C2)N=C=S)c2nnn(Cc3ccccc3Cl)c2n1

InChI Key InChIKey=JHNANFXRLRUBRS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419286   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419286(5-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3-isoth...)
Affinity DataKi:  1.36E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419286(5-tert-Butyl-3-[(2-chlorophenyl)methyl]-7-(3-isoth...)
Affinity DataKi:  5.64E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent