BDBM419144 N-(4-ethylphenyl)-3- hydroxymethyl-N-isobutyl- 4-(tetrahydropyran-4- ylmethanesulfinyl)benzene- sulfonamide::US10457637, Compound 15

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(c(CO)c1)S(=O)CC1CCOCC1

InChI Key InChIKey=NZHOKNBNRBCIEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419144   

TargetNuclear receptor ROR-gamma(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM419144(N-(4-ethylphenyl)-3- hydroxymethyl-N-isobutyl- 4-(...)
Affinity DataIC50: 550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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