BDBM4191 1,6-naphthyridin-2(1H)-one deriv. 8f::3-(2,6-Dichlorophenyl)-7-[[4-(diethylamino)butyl]amino]-1,6-naphthyridin-2(1H)-one::3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)butyl]amino}-1,2-dihydro-1,6-naphthyridin-2-one

SMILES CCN(CC)CCCCNc1cc2[nH]c(=O)c(cc2cn1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=OMTMSMIIXGDMJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4191   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4191(3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)butyl]a...)
Affinity DataIC50: 1.10E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4191(3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)butyl]a...)
Affinity DataIC50: 170nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4191(3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)butyl]a...)
Affinity DataIC50: 42nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed