BDBM418970 US10450301, Example 49

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3CN(CCc3cc2F)S(=O)(=O)N(C)C)n1

InChI Key InChIKey=ITXISCWSVDRGMN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418970   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM418970(US10450301, Example 49)Copy SMILESCopy InChI

Affinity DataIC50: 5.5nMAssay Description:HTRF KinEASE-STK is a generic method for measuring serine/threonine kinase activities using a time-resolved fluorescence resonance energy transfer (T...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details
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