BDBM418814 N-methyl-N-[3-({[2-{[4-(1H-tetrazol-5- yl)phenyl]amino}-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)pyridin-2- yl]methanesulfonamide (314)::US10450297, Example 314

SMILES CN(c1ncccc1CNc1nc(Nc2ccc(cc2)-c2nnn[nH]2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=REOAITYOMABWGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418814   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418814(N-methyl-N-[3-({[2-{[4-(1H-tetrazol-5- yl)phenyl]a...)
Affinity DataIC50: 0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent