BDBM418534 8-(1,3-Dimethyl-1H-pyrazol- 4-yl)-1-(3-fluoro-5-methoxy- pyridin-4-yl)-7-methoxy-1,3- dihydroimidazo[4,5-c]- quinolin-2-one::US10457677, Example 129::US10975075, Example 129::US11608338, Example 129

SMILES COc1cncc(F)c1-n1c2c(cnc3cc(OC)c(cc23)-c2cn(C)nc2C)[nH]c1=O

InChI Key InChIKey=WPTCUSZOQYZURV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 418534   

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418534(8-(1,3-Dimethyl-1H-pyrazol- 4-yl)-1-(3-fluoro-5-me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418534(8-(1,3-Dimethyl-1H-pyrazol- 4-yl)-1-(3-fluoro-5-me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418534(8-(1,3-Dimethyl-1H-pyrazol- 4-yl)-1-(3-fluoro-5-me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent