BDBM418502 1-[3-Fluoro-5-(2-methoxy- ethoxy)-2-pyridyl]-7- methoxy-3-methyl-8-(1- methylpyrazol-4-yl)imidazo- [4,5-c]quinolin-2-one::US10457677, Example 66::US10975075, Example 66::US11608338, Example 66

SMILES COCCOc1cnc(c(F)c1)-n1c2c(cnc3cc(OC)c(cc23)-c2cnn(C)c2)n(C)c1=O

InChI Key InChIKey=IKTWUKSXLCPALF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 418502   

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418502(1-[3-Fluoro-5-(2-methoxy- ethoxy)-2-pyridyl]-7- me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418502(1-[3-Fluoro-5-(2-methoxy- ethoxy)-2-pyridyl]-7- me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418502(1-[3-Fluoro-5-(2-methoxy- ethoxy)-2-pyridyl]-7- me...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent