BDBM418501 8-(3-Amino-1H-pyrazol-5- yl)-1-(3-fluoro-2-pyridyl)-7- methoxy-3-methyl-imidazo- [4,5-c]quinolin-2-one::US10457677, Example 65::US10975075, Example 65::US11608338, Example 65

SMILES COc1cc2ncc3n(C)c(=O)n(-c4ncccc4F)c3c2cc1-c1cc(N)n[nH]1

InChI Key InChIKey=AWPIOVFMFKDFFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 418501   

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418501(8-(3-Amino-1H-pyrazol-5- yl)-1-(3-fluoro-2-pyridyl...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418501(8-(3-Amino-1H-pyrazol-5- yl)-1-(3-fluoro-2-pyridyl...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetSerine-protein kinase ATM(Human)
Merck Patent

US Patent
LigandPNGBDBM418501(8-(3-Amino-1H-pyrazol-5- yl)-1-(3-fluoro-2-pyridyl...)
Affinity DataIC50: 1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent