BDBM415741 1-(4-(2- aminopyrimidin-4- yl)-3-chlorophenyl)- 3-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-6- yl)urea::US10442808, Example 23

SMILES CC(C)c1c(NC(=O)Nc2ccc(c(Cl)c2)-c2ccnc(N)n2)cnc2cc(Cl)nn12

InChI Key InChIKey=HEPFSWGYWADFMC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415741   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Human)
Novartis

US Patent

LigandBDBM415741(US10442808, Example 23 | 1-(4-(2- aminopyrimidin-4...)Copy SMILESCopy InChI

Affinity DataIC50: 0.00400nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2020
Entry Details
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