BDBM41563 US8871728, 167e

SMILES Oc1cccn(CCCCCn2cc(nn2)-c2cccc(c2)C#N)c1=S

InChI Key InChIKey=QQYCFXUASOHQCY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 41563   

TargetHistone deacetylase 6(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41563(US8871728, 167e)
Affinity DataIC50: 356nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41563(US8871728, 167e)
Affinity DataIC50: 2.83E+3nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41563(US8871728, 167e)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of HDAC8 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacFGC as substrate after 60 mins by SAMDI mas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41563(US8871728, 167e)
Affinity DataIC50: 356nMAssay Description:Inhibition of HDAC6 (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacYGC as substrate after 60 mins by SAMDI mass spectrometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM41563(US8871728, 167e)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacYGC as substrate after 60 mins by SAMDI mass spectrometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed