BDBM41549 US8871728, 162e

SMILES Oc1cccn(CCCCCCn2cc(nn2)-c2ccccc2)c1=S

InChI Key InChIKey=WOLPFDCMYOFWMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 41549   

TargetHistone deacetylase 8(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41549(US8871728, 162e)
Affinity DataIC50: 6.79E+3nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Georgia Tech Research

US Patent
LigandPNGBDBM41549(US8871728, 162e)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibition of HDAC8 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacFGC as substrate after 60 mins by SAMDI mas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed