BDBM415449 3-Ethyl-5-methyl-1-(oxetan-2-ylmethyl)-6-[(2-oxoimidazolidin-1-yl)methyl]thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione (Enantiomer 1)::US10428083, Example 66

SMILES CCn1c(=O)n(CC2CCO2)c2sc(CN3CCNC3=O)c(C)c2c1=O

InChI Key InChIKey=CDWIRFUAQXSUGR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 415449   

TargetAdenosine receptor A2b(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(US10428083, Example 66 | 3-Ethyl-5-methyl-1-(oxeta...)
Affinity DataKi:  5.20nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
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TargetAdenosine receptor A2a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(US10428083, Example 66 | 3-Ethyl-5-methyl-1-(oxeta...)
Affinity DataKi:  280nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(US10428083, Example 66 | 3-Ethyl-5-methyl-1-(oxeta...)
Affinity DataKi:  950nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415449(US10428083, Example 66 | 3-Ethyl-5-methyl-1-(oxeta...)
Affinity DataKi:  6.80E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent