BDBM415406 Intermediate 1-1-3::US10428063, Example 6

SMILES CC(C)(C)OC(=O)N1CCc2[nH]c(c(Nc3ccccc3)c2C1=O)-c1ccncc1

InChI Key InChIKey=GJVRUUHMZUPZBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415406   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415406(US10428063, Example 6 | Intermediate 1-1-3)
Affinity DataIC50: 10.9nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent