BDBM415402 Intermediate 1-1-2::US10428063, Example 2

SMILES O=C1NCCc2[nH]c(c(Nc3ccccc3)c12)-c1ccncc1

InChI Key InChIKey=MTBRQOGPXZHFAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415402   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415402(US10428063, Example 2 | Intermediate 1-1-2)
Affinity DataIC50: 7.89nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent