BDBM415357 Preparation of N-{4-[4′-oxo-3′-(phenylamino)-1′,4′,5′,7′-tetrahydrospiro[cyclopropane-1,6′-indol]-2′-yl]pyridin-2-yl}-1,3-oxazole-4-carboxamide::US10428044, Example 470

SMILES O=C(Nc1cc(ccn1)-c1[nH]c2CC3(CC3)CC(=O)c2c1Nc1ccccc1)c1cocn1

InChI Key InChIKey=IDBABOSHMWLZOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415357   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415357(US10428044, Example 470 | Preparation of N-{4-[4&#...)
Affinity DataIC50: 4.49nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
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Date in BDB:
8/17/2020
Entry Details
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