BDBM415108 Preparation of 2′-(3-fluoropyridin-4-yl)-3′-(phenylamino)-1′,7′-dihydrospiro[cyclopropane-1,6′-indol]-4′(5′H)-one::US10428044, Example 208

SMILES Fc1cnccc1-c1[nH]c2CC3(CC3)CC(=O)c2c1Nc1ccccc1

InChI Key InChIKey=BLTIOYPDMYXIPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415108   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415108(Preparation of 2′-(3-fluoropyridin-4-yl)-3&#...)
Affinity DataIC50: 6.39nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
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Date in BDB:
8/17/2020
Entry Details
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