BDBM415 Dihydropyran-2-one deriv. 20::N-(4-{[5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]-6-methyl-2-oxo-5,6-dihydro-2H-pyran-3-yl}sulfanyl)-2-methylphenyl]sulfamoyl}phenyl)acetamide

SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1cc(c(SC2C(=O)CC(C)(CCc3ccc(O)cc3)OC2=O)cc1C)C(C)(C)C

InChI Key InChIKey=GGDHDGAZQSBJMN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM415(N-(4-{[5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyp...)
Affinity DatapH: 6.2 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2004
Entry Details Article
PubMed